CZC 24832 (50 MG)
货号：
4674/50 基本售价：
15545.9 元 规格：
50 mg
产品信息
概述| 货号 | 4674/50 |
| 别名 | 5-(2-Amino-8-fluoro[1,2,4]triazolo[1,5-a]pyridin-6-yl)-N-(1,1-dimethylethyl)-3-pyridinesulfonamide |
性能| 供应商 | Tocris |
| 生物活性 | Selective inhibitor of PI 3-kinase γ(IC50 = 1.0 μM in a PI 3-Kγ-dependent fMLP-induced neutrophil migration assay). Exhibits limited off-target effects in kinome profiling of 154 identified lipid and protein kinases and 922 other proteins. Orally effective in a rodent model of inflammatory disease. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 364.4 |
| 分子式 | C15H17FN6O2< |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| 参考文献 | Bergaminiet al (2012) A selective inhibitor reveals PI3Kγ dependence of T(H)17 cell differentiation. Nat.Chem.Biol. 8 576. PMID: 22544264. |
