| 货号 | 3063/50 |
| 别名 | 1-(1,1-Dimethylethyl)-3-(1-naphthal |
| 供应商 | Tocris |
| 生物活性 | Selective inhibitor of src family kinases v-Src and c-Fyn as well as the tyrosine kinase c-Abl. (IC50 values are 1.0, 0.6, 0.6, 18 and 22 μM for v-Src, c-Fyn, c-Abl, CDK2 and CAMK II respectively). Preferentially inhibits mutant over wild-type kinases (IC50 values are 1.5 vs 1000 nM for I338G v-src and v-src respectively). |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 317.39 |
| 分子式 | C19H19N5 |
| 可溶性/溶解性 | Soluble to 20 mM in DMSO |
| CAS号 | 221243-82-9 |
| 参考文献 | Bishopet al (2000) A chemical switch for inhibitor-sensitive alleles of any protein kinase. Nature 407 395. PMID: 11014197. Bishopet al (1999) Generation of monospecific nanomolar tyrosine kinase inhibitors via a chemical genetic approach. J.Am.Chem.Soc. 121627. |