货号 | 0337/50 |
别名 | (S)-α-Methyl-4-carboxyphenylglycine |
供应商 | Tocris |
生物活性 | Active isomer of (RS)-MCPG (Cat. No. 0336). Non-selective group I/group II metabotropic glutamate receptor antagonist. Also available as part of the Group I mGlu Receptor Tocriset™, Group II mGlu Receptor Tocriset™ and Mixed mGlu Receptor Tocriset™. |
运输条件 | Blue Ice |
存放说明 | Ambient |
纯度 | >99 % |
计算分子量 | 209.2 |
分子式 | C10H11NO4 |
可溶性/溶解性 | Soluble to 100 mM in 1.1eq. NaOH |
CAS号 | 150145-89-4 |
参考文献 | Bordiet al (1996) Effects of the metabotropic glutamate receptor antagonist MCPG on spatial and context-specific learning. Neuropharmacology 35 1557. PMID: 9025103. Sekiyamaet al (1996) Structure-activity relationships of new agonists and antagonists of different metabotropic glutamate receptor subtypes. Br. J. Pharmacol. 117 1493. PMID: 8730745. Collingridge and Watkins (1994) Phenylglycine derivatives as metabotropic glutamate receptor antagonists. TiPS 15 333. PMID: 7992387. Janeet al (1993) Stereospecific antagonism by (+)-α-methyl-4-carboxyphenylglycine (MCPG) of 1S,3R-ACPD induced effects in neonatal rat motoneurones and rat thalamic neurones. Neuropharmacology 32 725. PMID: 7689710. |