| 货号 | 20752-5mg |
| 描述 | Dinactin is a macrotetrolide antibiotic that acts as an ionophore for monovalent cations, such as K+, NH4+, and Rb+.1 It is commonly used to study membrane properties.1,2 Dinactin is a component of a macrotetralide-rich antifungal mixture produced by Streptomyces.3 Dinactin inhibits T-cell proliferation and cytokine production in vitro and reduces pulmonary eosinophilia in antigen-challenged mice.4 |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Laprade, R.,Grenier, F.,Pagé-Dansereau, M., et al. Carrier-mediated ion transport in lipid bilayer membranes. Can. J. Biochem. Cell Biol. 62(8), 738-751 (1984). 2.Lapointe, J.-Y. and Laprade, R. Kinetics of carrier-mediated ion transport in two new types of solvent-free lipid bilayers. Biophys. J. 39(2), 141-150 (1982). 3.Silva, L.J.,Crevelin, E.J.,Souza, W.R., et al. Streptomyces araujoniae Produces a Multiantibiotic Complex with Ionophoric Properties to Control Botrytis cinerea. Phytopathology 104(12), 1298-1305 (2014). 4.Umland, S.P.,Shah, H.,Jakway, J.P., et al. Effects of cyclosporin A and dinactin on T-cell proliferation, interleukin-5 production, and murine pulmonary inflammation. Am. J. Respir. Cell Mol. Biol. 20(3), 481-492 (1999). | |
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 765 |
| 分子式 | C42H68O12 |
| CAS号 | 20261-85-2 |
| 稳定性 | ≥ 2 years |
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