货号 | 4184/50 |
别名 | (2R,4S)-4-[[[3,5-bis(Trifluoromethy |
供应商 | Tocris |
生物活性 | Inhibitor of cholesteryl ester transfer protein (CETP). Also impairs endothelial function in vivo; induces hypertension and inhibits acetylcholine-induced vasodilation in rabbit central ear artery. |
运输条件 | Blue Ice |
存放说明 | Ambient |
纯度 | >99 % |
计算分子量 | 600.47 |
分子式 | C26H25F9N2 |
可溶性/溶解性 | Soluble to 50 mM in DMSO |
参考文献 | Connellyet al (2010) Torcetrapib produces endothelial dysfunction independent of cholesteryl ester transfer protein inhibition. J.Cardiovascular Pharmacol. 55 459. PMID: 20051879. Forrestet al (2008) Torcetrapib-induced blood pressure elevation is independent of CETP inhibition and is accompanied by increasing circulating levels of aldosterone. Br.J.Pharmacol. 154 1465. PMID: 18536749. |