SGX 523 (50 MG)
货号：
5356/50 基本售价：
14951.1 元 规格：
50 mg
产品信息
概述| 货号 | 5356/50 |
| 别名 | 6-[[6-(1-Methyl-1H-pyrazol-4-yl)-1,2,4-triazolo[4,3-b]pyridazin-3-yl]thio]quinoline |
性能| 供应商 | Tocris |
| 生物活性 | Potent and selective c-MET kinase inhibitor (IC50 = 4nM). Exhibits minimal inhibition against a panel of 213 other protein kinases (at 1 μM). Suppresses growth of tumor xenografts derived from human glioblastoma, lung and gastric cancer cells. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 359.41 |
| 分子式 | C18H13N7S |
| 可溶性/溶解性 | Soluble to 20 mM in DMSO |
| 参考文献 | Buchananet al (2009) SGX523 is an exquisitely selective, ATP-competitive inhibitor of the MET receptor tyrosine kinase with antitumor activity in vivo. Mol.Cancer.Ther. 8 3181. PMID: 19934279. |
