AC 4 (50 MG)
货号：
5464/50 基本售价：
14951.1 元 规格：
50 mg
产品信息
概述| 货号 | 5464/50 |
| 别名 | 1,3,4,5-Tetrahydro-7,8-dihydro-N-[2-[4-[2-[4-(trifluoromethyl)phenyl]diazenyl]phenyl]ethyl]-2H-2-benzazepine-2-carbothioamide |
性能| 供应商 | Tocris |
| 生物活性 | Photoswitchable TRPV1 channel blocker (IC50 = 3.1 μM). Acts as an antagonist in trans conformation during voltage gated activation. Also acts as an antagonist in the cis formation during capsaicin-induced TRPV1 currents. Switches conformation from cistotrans at 440 nm and transtocis at 360 nm. Allows photoswitchable antagonist and an agonist to be applied at the same time. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 514.56 |
| 分子式 | C26H25F3N4 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 20 mM in water with gentle warming |
| 参考文献 | Steinet al (2013) Optical control of TRPV1 channels. Angew.Chem.Int.Ed.Engl. 52 9845. PMID: 23873837. |
