Isoliquiritigenin
货号：
10739-50mg 基本售价：
14700.0 元 规格：
50 mg
产品信息
概述| 货号 | 10739-50mg |
| 描述 | Isoliquiritigenin (ISL) is a flavonoid found in licorice root and several other plants that displays antioxidant, anti-inflammatory, and antitumor activities as well as hepatoprotection against steatosis-induced oxidative stress.1,2,3 ISL induces quinone reductase-1, a phase II enzyme that deactivates radicals and electrophiles, with a concentration required to double activity (CD) value of 1.8 μM in mouse hepatoma cells.2 |
| 别名 | GU 17;ISL; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Kim, D.C.,Choi, S.-Y.S.,Kim, S.H., et al. Isoliquiritigenin selectivity inhibits H2 histamine receptor signaling. Molecular Pharmacology 70(2), 493-500 (2006).
2.Cuendet, M.,Oteham, S.P.,Moon, R.C., et al. Quinone Reductase Induction as a biomarker for cancer chemoprevention. Journal of Natural Products 69(3), 460-463 (2006).
3.Kim, Y.M.,Kim, T.H.,Kim, Y.W., et al. Inhibition of liver X receptor-α-dependent hepatic steatosis by isoliquiritigenin; a licorice antioxidant flavonoid, as mediated by JNK1 inhibition. Free Radical Biology & Medicine 49, 1722-1734 (2010).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 256.3 |
| 分子式 | C15H12O4 |
| CAS号 | 961-29-5 |
| 稳定性 | ≥ 2 years |
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