SSR 146977 hydrochloride (50 MG)
货号：
3297/50 基本售价：
14653.6 元 规格：
50 mg
产品信息
概述| 货号 | 3297/50 |
| 别名 | N1-[1-3-[(3R)-1-Benzoyl-3-(3-(3,4-dichlorophenyl)-3-piperidinyl]propyl]-4-phenyl-piperidinyl]-N,N-dimethylurea hydrochloride |
性能| 供应商 | Tocris |
| 生物活性 | Potent and selective NK3 receptor antagonist (Ki values are 0.26 and 19.3 nM in CHO cells expressing the human NK3 and NK2 receptor respectively). Also inhibits senktide-induced inositol monophosphate formation and intracellular calcium mobilization (IC50 = 10 nM). |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 658.11 |
| 分子式 | C35H42Cl2N4< |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| 参考文献 | Emonds-Altet al (2002) Biochemical and pharmacological activities of SSR 146977, a new potent nonpeptide tachykinin NK3 receptor antagonist. Can.J.Physiol.Pharmacol. 80 482. PMID: 12056557. |
