| 货号 | 4086/50 |
| 别名 | 4-[[[7-(Diethylamino)-2,4-dioxo-2H- |
| 供应商 | Tocris |
| 生物活性 | Potent fluorescent inhibitor of human acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) (IC50 values are 280 pM and 16 nM respectively). Targets and labels β-amyloid plaques in histochemical analysis. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >97 % |
| 计算分子量 | 589.68 |
| 分子式 | C35H35N5O4 |
| 可溶性/溶解性 | Soluble to 50 mM in DMSO |
| 参考文献 | Kaczaet al (2010) In vivo labelling of hippocampal beta-amyloid in triple-transgenic mice with a fluorescent acetylcholinesterase inhibitor released from nanoparticles. Eur.J.Neurosci. 31 99. PMID: 20092557. Elsinghorstet al (2009) A gorge-spanning, high-affinity cholinesterase inhibitor to explore β-amyloid plaques. Org.Biomol.Chem. 7 3940. PMID: 19763296. |