| 货号 | 1044/50 |
| 别名 | 2,3-Dioxo-6-nitro-1,2,3,4-tetrahydr |
| 供应商 | Tocris |
| 生物活性 | Potent, selective and competitive AMPA receptor antagonist. Neuroprotective and anticonvulsant; active in vivo. More water soluble disodium salt of NBQX (Cat. No. 0373). Also available as part of the AMPA Receptor Tocriset™. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 380.24 |
| 分子式 | C12H6N4O6SNa2 |
| 可溶性/溶解性 | Soluble to 100 mM in water |
| CAS号 | 118876-58-7 |
| 参考文献 | Nambaet al (1994) Antiepileptogenic and anticonvulsant effects of NBQX, a selective AMPA receptor antagonist, in the rat kindling model of epilepsy. Brain Res. 638 36. PMID: 8199874. Sheardownet al (1993) The pharmacology of AMPA receptors and their antagonists. Stroke 24 146. PMID: 7504337. Gillet al (1992) The neuroprotective actions of 2,3-dihydroxy-6-nitro-7-sulfamoylbenzo(f)quinoxaline (NBQX) in a rat focal ischaemia model. Brain Res. 580 35. PMID: 1504814. Zeman and Lodg (1992) Pharmacological characterization of non-NMDA subtypes of glutamate receptors in the neonatal rat hemisected spinal cord in vitro. Br.J.Pharmacol. 106 367. PMID: 1382781. |