ISOX DUAL ( )
货号：
5806/50 基本售价：
14356.2 元 规格：
50 mg
产品信息
概述| 货号 | 5806/50 |
| 别名 | [3-[4-[2-[5-(Dimethyl-1,2-oxazol-4-yl)-1-[2-(morpholin-4-yl)ethyl]-1H-1,3-benzodiazol-2-yl]ethyl]phenoxy]propyl]dimethylamine |
性能| 供应商 | Tocris |
| 生物活性 | Dual CBP/p300 and BRD4 bromodomain inhibitor (IC50 values are 0.65 and 1.5 μM for CBP and BRD4 respectively). Downregulates IL-6,IL-1βandIFN-β in macrophages. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 531.69 |
| 分子式 | C31H41N5O3 |
| 可溶性/溶解性 | Soluble to 100 mM in 1eq. HCl and to 50 mM in DMSO |
| 参考文献 | Chekler (2015) Transcriptional profiling of a selective CREB binding protein bromodomain inhibitor highlights therapeutic opportunities. Chem.Biol. 22 1588. PMID: 26670081. |
