MS 023 dihydrochloride ( )
货号：
5713/50 基本售价：
14058.8 元 规格：
50 mg
产品信息
概述| 货号 | 5713/50 |
| 别名 | N1-Methyl-N1-[[4-[4-(1-methylethoxy)phenyl]-1H-pyrrol-3-yl]methyl]-1,2-ethanediamine dihydrochloride |
性能| 供应商 | Tocris |
| 生物活性 | Potent and selective type I PRMT inhibitor (IC50 values are 8, 8, 30, 83 and 119 nM for PRMT6, PRMT8, PRMT1, PRMT4 and PRMT3, respectively). Exhibits no significant activity against type II and III PRMTs, PKMTs, DNMTs, KDMs and reader proteins. Reduces global arginine asymmetric dimethylation levels in vitro. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 360.32 |
| 分子式 | C17H25N3O.2HCl |
| 可溶性/溶解性 | Soluble to 100 mM in water and to 100 mM in DMSO |
| 参考文献 | Eramet al (2016) A potent, selective, and cell-active inhibitor of human type I protein arginine methyltransferases. ACS Chem.Biol. 11 772. PMID: 26598975. |
