U-44069
货号：
16440-10mg 基本售价：
14000.0 元 规格：
10 mg
产品信息
概述| 货号 | 16440-10mg |
| 描述 | U-44069 is a stable analog of the endoperoxide PGH2 (Item No. 17020) and a TP receptor agonist. It stimulates shape change in human platelets without a measurable increase in [Ca2+] with an EC50 value of 1.8 nM.1 U-44069 has an EC50 value of 3 µM and 54 nM for platelet aggregation and phosphatidate formation in human platelets, respectively.2 |
| 别名 | 9,11-dideoxy-9α,11α-epoxymethano PGF2α;9,11-dideoxy-9α,11α-epoxymethano Prostaglandin F2α;9,11-epoxymethano Prostaglandin H2; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Simpson, A.W.M.,Hallam, T.J. and Rink, T.J. Low concentrations of the stable prostaglandin endoperoxide U44069 stimulate shape change in quin2-loaded platelets without a measurable increase in [Ca2+]i. FEBS Letters 201, 301-305 (1986).
2.Pollock, W.K.,Armstrong, R.A.,Brydon, L.J., et al. Thromboxane-induced phosphatidate formation in human platelets. Relationship to receptor occupancy and to changes in cytosolic free calcium. Biochemistry Journal 219, 833-842 (1984).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 350.5 |
| 分子式 | C21H34O4 |
| CAS号 | 56985-32-1 |
| 稳定性 | ≥ 2 years |
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