货号 | 0254/50 |
别名 | (S)-α-Amino-3-hydroxy-5-methyl-4-iso |
供应商 | Tocris |
生物活性 | Active enantiomer of AMPA (EC50 = 3.5 μM). Also available as part of the AMPA Receptor Tocriset™ (Cat. No. 1822). NPEC-caged-(S)-AMPA (Cat. No. 3840), inactive enantiomer (R)-AMPA (Cat. No. 0253) and racemate (RS)-AMPA (Cat. No. 0169) are also available. |
运输条件 | Blue Ice |
存放说明 | Ambient |
纯度 | >99 % |
计算分子量 | 186.17 |
分子式 | C7H10N2O4 |
可溶性/溶解性 | Soluble to 100 mM in water |
CAS号 | 83643-88-3 |
参考文献 | Falchet al (1998) Heteroaryl analogues of AMPA. 2. Synthesis, absolute stereochemistry, photochemistry, and structure-activity relationships. J.Med.Chem. 41 2513. PMID: 9651156. Lauridsenet al (1985) Ibotenic acid analogues. Synthesis, molecular flexibility, and in vitro activity of agonists and antagonists at central glutamic acid receptors. J.Med.Chem. 28 668. PMID: 2859375. Hansenet al (1983) Enzymic resolution and binding to rat brain membranes of the glutamic acid agonist α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid. J.Med.Chem. 26 901. PMID: 6133955. |