| 货号 | 20220-2.5mg |
| 描述 | Trichostatin C is a glycosylated derivative of trichostatin A (Item No. 89730), the antifungal antibiotic that reversibly inhibits histone deacetylase.1 Trichostatin C is reported to be the first example of a glucopyranosyl hydroxamate identified in nature.2 It has been shown to induce the differentiation of a mouse erythroleukemia cell line and to increase histone H4 acetylation in B cells, though at higher concentrations than trichostatin A.3,4 |
| 别名 | Antibiotic 145-A; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Mori, K. and Koseki, K. Synthesis of trichostatin A, a potent differentiation inducer of friend leukemic cells, and its antipode. Tetrahedron 44, 6013-6020 (1988). 2.Tsuji, N. and Kobayashi, M. richostatin C, a glucopyranosyl hydroxamate. J.Antibiot.(Tokyo) 31(10), 939-944 (1978). 3.Yoshida, M.,Iwamoto, Y.,Uozumi, T., et al. Trichostatin C, a new inducer of differentiation of friend leukemic cells. Agric.Biol.Chem. 49(2), 563-565 (1985). 4.Kohge, T.,Gohda, E.,Okamura, T., et al. Promotion of antigen-specific antibody production in murine B cells by a moderate increase in histone acetylation. Biochem.Pharmacol. 56(10), 1359-1364 (1998). | |
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 464.5 |
| 分子式 | C23H32N2O8 |
| CAS号 | 68676-88-0 |
| 稳定性 | ≥ 2 years |
| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |