Ciprostene (calcium salt)
货号：
18216-10mg 基本售价：
13888.0 元 规格：
10 mg
产品信息
概述| 货号 | 18216-10mg |
| 描述 | Ciprostene is the 9β-methyl analog of carbaprostacyclin and a stable analog of PGI2. Ciprostene exhibits biological activity similar to PGI2, but is 30-fold less potent. In patas monkeys, ciprostene induces hypotension and causes tachycardia when administered at a dose of 0.16 µg/kg/min.1 In addition, ciprostene inhibits ADP-induced platelet aggregation ex vivoandin vitro with ID50 values of 9.1 µg/kg/min and 60 ng/ml, respectively.1,2 |
| 别名 | Ciprostene calcium;U-61431F; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Allan, G.,Follenfant, M.J.,Lidbury, P., et al. The cardiovascular and platelet actions of 9β-methyl carbacyclin (ciprostene), a chemically stable analogue of prostacyclin, in the dog and monkey. British Journal of Pharmacology 85, 547-555 (1985).
2.Aristoff, P.A.,Johnson, P.D., and Harrison, A.W. Synthesis of 9-substituted carbacyclin analogues. J. Org. Chem. 48, 5341-5348 (1983).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 767.1 |
| 分子式 | [C22H35O4]2 • Ca2+ |
| CAS号 | 81703-55-1 |
| 稳定性 | ≥ 6 months |
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