Resolvin D4
货号：
13835-100ug 基本售价：
13832.0 元 规格：
100 ug
产品信息
概述| 货号 | 13835-100ug |
| 描述 | Resolvin D4 (RvD4) is a specialized pro-resolving mediator derived from docosahexaenoic acid (Item No. 90310).1 It has been detected in human milk, in the dorsal pouch of mice before and after infection with S. aureus, and in untreated tissues from humans, mice, and sardines.2,3 RvD4, at 10 ng/mouse, reduces neutrophil infiltration in zymosan A-induced peritonitis and, at 200 ng/mouse, diminishes neutrophil infiltration in response to S. aureusinfection.3 With isolated cells, RvD4 promotes phagocytosis of bacteria, opsonized zymosan A, and apoptotic neutrophils by human macrophages.3 It also promotes the clearance of apoptotic neutrophils by human fibroblasts.3 |
| 别名 | RvD4; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Serhan, C.N. and Savill, J. Resolution of inflammation: The beginning programs the end. Nature Immunology 6(12), 1191-1197 (2005).
2.Arnardottir, H.,Orr, S.K.,Dalli, J., et al. Human milk proresolving mediators stimulate resolution of acute inflammation. Mucosal. Immunol. 9(3), 757-766 (2016).
3.Winkler, J.W.,Orr, S.K.,Dalli, J., et al. Resolvin D4 stereoassignment and its novel actions in host protection and bacterial clearance. Sci.Rep. 6, (2016).
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| 运输条件 | Dry ice in continental US; may vary elsewhere |
| 存放说明 | -80 |
| 纯度 | ≥95% |
| 计算分子量 | 376.5 |
| 分子式 | C22H32O5 |
| CAS号 | 1025684-60-9 |
| 稳定性 | ≥ 1 year |
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