| 货号 | 2764/50 |
| 别名 | N-(Piperidin-1-yl)-1-(2,4-dichlorop |
| 供应商 | Tocris |
| 生物活性 | Highly selective CB2 receptor agonist; Ki values are 0.037 and 363 nM for CB2 and CB1 receptors respectively. Increases P-ERK1/2 expression in HL-60 cells in vitro. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 441.35 |
| 分子式 | C23H22Cl2N4< |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| 参考文献 | Tschopet al (2009) The cannabinoid receptor 2 is critical for the host response to sepsis. J.Immunol. 183 499. PMID: 19525393. Murinedduet al (2006) Tricyclic pyrazoles. 4. Synthesis and biological evaluation of analogues of the robust and selective CB2 cannabinoid ligand 1-(2',4'-dichlorophenyl)-6-methyl-N-piperidin-1-yl-1,4-dihydroindeno[1,2-c]pyrazole-3-carboxamide. J.Med.Chem. 49 7502. PMID: 17149879. |