YK 4-279 (50 MG)
货号:
4067/50 基本售价:
13761.3 元 规格:
50 mg
产品信息
概述货号 | 4067/50 |
别名 | 4,7-Dichloro-1,3-dihydro-3-hydroxy-3-[2-(4-methoxyphenyl)-2-oxoethyl]-2H-indol-2-one |
性能供应商 | Tocris |
生物活性 | Inhibitor of RNA Helicase A (RHA) binding to the oncogenic transciption factor EWS-FLI1. Inhibits Ewing's sarcoma family tumor (ESFT) cell growth; induces apoptosis. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
纯度 | >99 % |
计算分子量 | 366.2 |
分子式 | C17H13Cl2NO4 |
可溶性/溶解性 | Soluble to 100 mM in DMSO |
参考文献 | Erkizanet al (2009) Small molecule selected to disrupt oncogenic protein EWS-FLI1 interaction with RNA helicase A inhibits Ewing's sarcoma. Nat.Med. 15 750. PMID: 19584866. |