TC-N 1752 (50 MG)
货号：
4435/50 基本售价：
13761.3 元 规格：
50 mg
产品信息
概述| 货号 | 4435/50 |
| 别名 | N-[2-Methyl-3-[[4-[4-[[4-(trifluoromethoxy)phenyl]methoxy]-1-piperidinyl]-1,3,5-triazin-2-yl]amino]phenyl]acetamide |
性能| 供应商 | Tocris |
| 生物活性 | Selective blocker of human NaV1.7 channels (IC50 values are 0.17, 0.3, 0.4 and 1.1 μM at hNaV1.7, hNaV1.3, hNaV1.4 and hNaV1.5 respectively). Also inhibits tetrodotoxin-sensitive sodium channels. Displays analgesic efficacy in the formalin pain model. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 516.52 |
| 分子式 | C25H27F3N6 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 10 mM in 1eq. HCl |
| 参考文献 | Bregmanet al (2011) Identification of a potent, state-dependent inhibitor of Nav1.7 with oral efficacy in the formalin model of persistent pain. J.Med.Chem. 54 4427. PMID: 21634377. |
