TC-A 2317 hydrochloride (50 MG)
货号：
4066/50 基本售价：
13761.3 元 规格：
50 mg
产品信息
概述| 货号 | 4066/50 |
| 别名 | 2-[(5-Hydroxy-1,5-dimethylhexyl)amino]-4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)amino]-3-pyridinecarbonitrile hydrochloride |
性能| 供应商 | Tocris |
| 生物活性 | Potent Aurora kinase A inhibitor (Ki = 1.2 nM compared to 101 nM for inhibition of Aurora kinase B). Selective over 60 other kinases (IC50 values > 1000 nM). Exhibits good cell permeability and antitumor activity. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 392.93 |
| 分子式 | C19H28N6O.HCl |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 50 mM in ethanol |
| 参考文献 | Andoet al (2010) 3-Cyano-6-(-5-methyl-3-pyrazoloamino)pyridines: Selective Aurora A kinase inhibitors. Bioorg.Med.Chem.Lett. 20 4709. PMID: 20573509. |
