STO-609 acetate (50 MG)
货号：
1551/50 基本售价：
13761.3 元 规格：
50 mg
产品信息
概述| 货号 | 1551/50 |
| 别名 | 7-Oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic acid acetate |
性能| 供应商 | Tocris |
| 生物活性 | Selective, cell-permeable inhibitor of Ca2+-calmodulin-dependent protein kinase kinase (Ki values are 80 and 15 ng/ml for inhibition of CaM-KKα and CaM-KKβ respectively); competes for the ATP-binding site. Displays > 80-fold selectivity over CaMK1, CaMK2, CaMK4, MLCK, PKC, PKA and p42 MAPK. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 374.35 |
| 分子式 | C19H10N2O3.C2H4O2 |
| 可溶性/溶解性 | Soluble to 45 mM in 100mM NaOH and to 10 mM in DMSO with sonication |
| CAS号 | 52029-86-4 |
| 参考文献 | Tokumitsuet al (2002) STO-609, a specific inhibitor of the Ca2+/calmodulin-dependent protein kinase kinase. J.Biol.Chem. 277 15813. PMID: 11867640. |
