| 货号 | 1529/50 |
| 别名 | 4-[(S)-[(2S,5R)-2,5-Dimethyl-4-(2-p |
| 供应商 | Tocris |
| 生物活性 | Potent and selective non-peptide δ-opioid receptor agonist (Ki = 0.63 nM). Displays > 8000-fold selectivity over μ-opioid receptors and is centrally active following systemic administration in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 419.61 |
| 分子式 | C27H37N3O |
| 可溶性/溶解性 | Soluble to 100 mM in 1eq. HCl |
| CAS号 | 178803-51-5 |
| 参考文献 | Neguset al (1998) Behavioral effects of the delta-selective opioid agonist SNC80 and related compounds in rhesus monkeys. J.Pharmacol.Exp.Ther. 286 362. PMID: 9655881. Calderonet al (1997) Probes for narcotic receptor mediated phenomena. 23. Synthesis, opioid receptor binding, and bioassay of the highly selective δ agonist (+)-4-[(αR)-α-((2S,5R)-4-allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]-N,N-diethylbenzamide (SNC 80) and related novel nonpeptide δ opioid receptor ligands. J.Med.Chem. 40 695. PMID: 9057856. Knappet al (1996) Structure-activity relationships for SNC80 and related compounds at cloned human deltaandmu opioid receptors. J.Pharmacol.Exp.Ther. 277 1284. PMID: 8667189. |