PHP 501 trifluoroacetate (50 MG)
货号：
4466/50 基本售价：
13761.3 元 规格：
50 mg
产品信息
概述| 货号 | 4466/50 |
| 别名 | 4-(5-[1,1'-Biphenyl]-3-yl-1-hydroxy-1H-pyrazol-4-yl)piperidine trifluoroacetate |
性能| 供应商 | Tocris |
| 生物活性 | Potent GABAA antagonist (Ki = 0.0028 μM at rat GABAA receptors; IC50 = 0.024 μM at human α1β2γ2GABAA-expressing tsA201 cells). Displays no inhibitory activity at hGAT-1, hGAT-2, hGAT-3 or hBGT-1 GABA transporters. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 433.42 |
| 分子式 | C20H21N3O.CF |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| 参考文献 | Mølleret al (2010) Novel 4-(piperidin-4-yl)-1-hydroxypyrazoles as gamma-aminobutyric acid(A) receptor ligands: synthesis, pharmacology, and structure-activity relationships. J.Med.Chem. 53 3417. PMID: 20355712. |
