| 货号 | 1378/50 |
| 别名 | (3S,4R)-3,4-dihydro-3-hydroxy-2,2-d |
| 供应商 | Tocris |
| 生物活性 | Active enantiomer of the prototypical Kir6 (KATP) channel opener cromakalim (Cat. No. 1377). Hypotensive and airways relaxant. IC50 = 490 nM in guinea pig trachea. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 286.33 |
| 分子式 | C16H18N2O3 |
| 可溶性/溶解性 | Soluble to 10 mM in DMSO |
| CAS号 | 94535-50-9 |
| 参考文献 | Noacket al (1992) Potassium channel modulation in rat portal vein by ATP depletion: a comparison with the effects of levcromakalim (BRL 38227). Br.J.Pharmacol. 107 945. PMID: 1467843. Tayloret al (1992) The inhibitory effects of cromakalim and its active enantiomer BRL 38227 against various agonists in guinea pig and human airways. J.Pharmacol.Exp.Ther. 261 429. PMID: 1578358. Buckleet al (1991) Synthesis and smooth muscle relaxant activity of a new series of potassium channel activators: 3-amido-1,1-dimethylindan-2-ols. J.Med.Chem. 34 919. PMID: 2002472. |