| 货号 | 2767/50 |
| 别名 | N-[(3R)-2,3-Dihydro-1-methyl-2-oxo- |
| 供应商 | Tocris |
| 生物活性 | Selective cholecystokinin receptor 2 (CCK2) antagonist (IC50 values are 2 and 280 nM at CCK2 and CCK1 receptors respectively) that is inactive at a range of other receptors including opiate, muscarinic acetylcholine, α- and β adrenergic, histamine, angiotensin and bradykinin receptors. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 398.46 |
| 分子式 | C24H22N4O2 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| CAS号 | 118101-09-0 |
| 参考文献 | Chunget al (2009) Cholecystokinin action on layer 6b neurons in somatosensory cortex. Brain Res. 1282 10. PMID: 19497313. Keeset al (1989) Benzodiazepine gastrin and brain cholecystokinin receptor ligands: L-365,260. J.Med.Chem. 32 13. PMID: 2909725. Lotti and Chang (1989) A new potent and selective non-peptide gastrin antagonist and brain cholecystokinin receptor (CCK-B) ligand: L-365,260. Eur.J.Pharmacol. 162 273. PMID: 2721567. |