| 货号 | 4242/50 |
| 别名 | 6-(4-Chlorophenyl)-3-[3-methoxy-4-[ |
| 供应商 | Tocris |
| 生物活性 | Selective melanin-concentrating hormone receptor 1 (MCH1) antagonist (IC50 = 9.3 nM). Displays antiobesity and antidepressant-like effects in rats and mice. Orally active. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 481.99 |
| 分子式 | C25H24ClN3O3 |
| 可溶性/溶解性 | Soluble to 25 mM in 1eq. HCl |
| 参考文献 | Gehlertet al (2009) Preclinical evaluation of melanin-concentrating hormone receptor 1 antagonism for the treatment of obesity and depression. J.Pharmacol.Exp.Ther. 329 429. PMID: 19182070. Riveraet al (2008) Melanin-concentrating hormone receptor 1 antagonists: a new perspective for the pharmacologic treatment of obesity. Curr.Med.Chem. 15 1025. PMID: 18393860. |