| 货号 | 3600/50 |
| 别名 | N-[2-[4-(2,3-Dihydro-2-oxo-1H-benzi |
| 供应商 | Tocris |
| 生物活性 | Potent phosholipase D (PLD) inhibitor (IC50 values are 20 and 25 nM for PLD2 and PLD1 respectively). Ameliorates PLD2-driven suppression of membrane ruffling and cell spreading. Orally available. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 457.93 |
| 分子式 | C23H24FN5O2< |
| 可溶性/溶解性 | Soluble to 50 mM in DMSO |
| 参考文献 | Suet al (2009) 5-fluoro-2-indolyl des-chlorohalopemide (FIPI), a phospholipase D pharmacological inhibitor that alters cell spreading and inhibits chemotaxis. Mol.Pharmcol. 7543. Monovichet al (2007) Optimization of halopemide for phospholipase D2 inhibition. Bioorg.Med.Chem.Lett. 17 2310. PMID: 17317170. |