货号 | 0102/50 |
别名 | D-(-)-2-Amino-4-phosphonobutyric acid |
供应商 | Tocris |
生物活性 | Broad spectrum excitatory amino acid receptor antagonist. Also agonist at the quisqualate-sensitized AP6 site in hippocampus where it is less potent than L-AP4. DL Mixture (Cat. No. 0101) and L-isomer (Cat. No. 0103) also available. |
运输条件 | Blue Ice |
存放说明 | Ambient |
纯度 | >98 % |
计算分子量 | 183.1 |
分子式 | C4H10NO5P |
可溶性/溶解性 | Soluble to 100 mM in 1eq. NaOH |
CAS号 | 78739-01-2 |
参考文献 | Schulteet al (1994) Utilization of the resolved L-isomer of 2-amino-6-phosphonhexanoic acid (L-AP6) as a selective agonist for a quisqualate-sensitized site in hippocampal CA1 pyramidal neurons. Brain Res. 649 203. PMID: 7953634. Davies and Watkins (1982) Actions of D and L forms of 2-amino-5-phosphonovalerate and 2-amino-4-phosphonobutyrate in the cat spinal cord. Brain Res. 235 378. PMID: 6145492. Evanset al (1982) The effect of a series of ω-phosphonic-α-carboxylic amino acids on electrically evoked and amino acid induced responses in isolated spinal cord preparations. Br.J.Pharmacol. 75 65. PMID: 7042024. |