| 货号 | 4543/50 |
| 别名 | 1-[[4-Ethyl-5-[5-(4-phenoxyphenyl)- |
| 供应商 | Tocris |
| 生物活性 | Sphingosine-1-phosphate receptor 1 (S1P1) agonist (EC50 = 4.0 nM). Exhibits 5000-fold selectivity for human S1P1 over S1P3. Displays efficacy in a rat adjuvant-induced arthritis model. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >97 % |
| 计算分子量 | 461.53 |
| 分子式 | C25H23N3O4 |
| 可溶性/溶解性 | Soluble to 5 mM in DMSO with gentle warming |
| 参考文献 | Nakamuraet al (2012) Synthesis and evaluation of CS-2100, a potent, orally active and S1P3-sparing S1P1 agonist. Eur.J.Med.Chem. 51 92. PMID: 22405291. Nakamuraet al (2012) Discovery of CS-2100, a potent, orally active and S1P3-sparing S1P1 agonist. Bioorg.Med.Chem.Lett. 22 1788. PMID: 22264485. |