Eicosapentaenoyl Ethanolamide-d4
货号：
9001835-5mg 基本售价：
13720.0 元 规格：
5 mg
产品信息
概述| 货号 | 9001835-5mg |
| 描述 | Eicosapentaenoyl ethanolamide (EPEA)-d4 contains four deuterium atoms at the 1, 1, 2, and 2 positions. It is intended for use as an internal standard for the quantification of EPEA by GC- or LC-mass spectrometry. Eicosapentaenoyl Ethanolamide (EPEA) is an N-acylethanolamide that inhibits dietary-restriction-induced lifespan extension in wild type and TOR pathway mutant nematodes.1 Produced endogenously from eicosapentaenoic acid, EPEA serves as a metabolic signal that couples nutrient availability with growth and lifespan. EPEA also has anti-inflammatory properties, suppressing the expression of IL-6 and MCP-1 in 3T3-L1 adipocytes in response to lipopolysaccharide.2 |
| 别名 | EPEA-d4; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Lucanic, M.,Held, J.M.,Vantipalli, M.C., et al. N-acylethanolamine signalling mediates the effect of diet on lifespan in Caenorhabditis elegans. Nature 473(7346), 226-229 (2011).
2.Balvers, M.G.,Verhoeckx, K.C.,Plastina, P., et al. Docosahexaenoic acid and eicosapentaenoic acid are converted by 3T3-L1 adipocytes to N-acyl ethanolamines with anti-inflammatory properties. Biochimica et Biophysica Acta 1801(10), 1107-1114 (2010).
|
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥99% deuterated forms (d1-d4) |
| 计算分子量 | 349.5 |
| 分子式 | C22H31D4NO2 |
| CAS号 | 946524-41-0 |
| 稳定性 | ≥ 1 year |
声明| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |
