Ternatin
货号：
20691-5mg 基本售价：
13608.0 元 规格：
5 mg
产品信息
概述| 货号 | 20691-5mg |
| 描述 | Ternatin is a cyclic heptapeptide first isolated from the mushroom C. versicolor that has been shown to have cytotoxic and anti-adipogenic effects in vitro.1 It inhibits adipogenesis with an IC50 value of 27 nM and becomes cytotoxic to 3T3-L1 mouse adipocytes at 10-fold higher concentrations.1 Ternatin is reported to inhibit HCT116 cell proliferation with an IC50 value of 71 nM.2 Note that this metabolite should not be confused with the plant flavonoid of the same name. |
| 别名 | 1,4,7,10,13,16,19-Heptaazacycloheneicosane;(-)-Ternatin; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Shimokawa, K.,Iwase, Y.,Yamada, K., et al. Synthesis and inhibitory effect on fat accumulation of (−)-ternatin derivatives modified in the beta-OH-D-Leu7 moiety. Org. Biomol. Chem. 6(1), 58-60 (2008).
2.Carelli, J.D.,Sethofer, S.G.,Smith, G.A., et al. Ternatin and improved synthetic variants kill cancer cells by targeting the elongation factor-1A ternary complex. eLife 4, (2015).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 738 |
| 分子式 | C37H67N7O8 |
| CAS号 | 148619-41-4 |
| 稳定性 | ≥ 2 years |
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