| 货号 | 14572-1g |
| 描述 | Citalopram is a selective serotonin reuptake inhibitor which is commonly prescribed as an antidepressant.1,2,3 It also acts as an antagonist of nicotinic acetylcholine receptors (IC50 = 0.93 µM).4 |
| 别名 | Bonitrile;Lu 10-171;Nitalapram;Prepram; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Milan, M.J.,Gobert, A.,Rivet, J.M., et al. Mirtazapine enhances frontocortical dopaminergic and corticolimbic adrenergic, but not serotonergic, transmission by blockade of α2-adrenergic and serotonin2C receptors: A comparison with citalopram. European Journal of Neuroscience 12(3), 1079-1095 (2000). 2.Boothman, L.J.,Mitchell, S.N. and Sharp, T. Investigation of the SSRI augmentation properties of 5-HT2 receptor antagonists using in vivo microdialysis. Neuropharmacology 50(6), 726-732 (2006). 3.Bymaster, F.P.,Zhang, W.,Carter, P.A., et al. Fluoxetine, but not other selective serotonin uptake inhibitors, increases norepinephrine and dopamine extracellular levels in prefrontal cortex. Psychopharmacology (Berl) 160(4), 353-361 (2002). 4.Shytle, R.D.,Silver, A.A.,Lukas, R.J., et al. Nicotinic acetylcholine receptors as targets for antidepressants. Molecular Psychiatry 7(6), 525-535 (2002). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 405.3 |
| 分子式 | C20H21FN2O • HBr |
| CAS号 | 59729-32-7 |
| 稳定性 | ≥ 2 years |
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