CAY10701
货号：
18906-1mg 基本售价：
13174.0 元 规格：
1 mg
产品信息
概述| 货号 | 18906-1mg |
| 描述 | CAY10701 is a 7-deazahypoxanthine analog that prevents microtubule formation, blocking the proliferation of HeLa and MCF-7 cells (GI50s = 22 and 38 nM, respectively).1 It also inhibits the growth of several different colorectal cancer cell lines (GI50 values range from 9 to 17 nM), while being at least 1,500-fold less effective against normal human fibroblast WI38 cells.1 CAY10701 is effective in vivo, reducing tumor volume in colorectal cell xenografts in mice without significantly altering body weight.1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Medellin, D.C.,Zhu, Q.,Scott, R., et al. Novel microtubule-targeting 7-deazahypoxanthines derived from marine alkaloid rigidins with potent in vitro and in vivo anticancer activities. J. Med. Chem. 59, 480-485 (2016).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 381.4 |
| 分子式 | C24H19N3O2 |
| CAS号 | 1616967-52-2 |
| 稳定性 | ≥ 2 years |
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