| 货号 | 21289-25mg |
| 描述 | Quercetin 3-O-glucuronide is a pharmacologically active flavonol glucuronide isolated from H. perforatum (St. John’s wort) that inhibits the α2c adrenergic receptor (Ki = 4,060 nM in hα2cpreparations).1,2,3 Quercetin 3-O-glucuronide (0.6 mg/kg) reduced the time rats spent immobile in the forced swim test, suggesting antidepressant-like properties, when given either acutely or chronically.4 It also reduced open field stress-induced hyperthermia in mice (at 1.2 mg/kg).5 |
| 别名 | Miquelianin;Quercetin 3-O-β-D-glucuronide; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Nahrstedt, A. and Butterweck, V. Biologically active and other chemical constituents of the herb of Hypericum perforatum L. Pharmacopsychiatry 30(Suppl 2), 129-134 (1997). 2.Nahrstedt, A. and Butterweck, V. Lessons learned from herbal medicinal products: The example of St. John’s Wort. J. Nat. Prod. 73(5), 1015-1021 (2010). 3.Butterweck, V.,Jürgenliemk, G.,Narstedt, A., et al. Flavonoids from Hypericum perforatum show antidepressant activity in the forced swimming test. Planta Med. 66(1), 3-6 (2000). 4.Grundmann, O.,Kelber, O. and Butterweck, V. Effects of St. John’s wort extract and single constituents on stress-induced hyperthermia in mice. Planta Med. 72(15), 1366-1371 (2006). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 478.4 |
| 分子式 | C21H18O13 |
| CAS号 | 22688-79-5 |
| 稳定性 | ≥ 2 years |
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