货号 | 19500-1mg |
描述 | Thromboxane B2(TXB2) is released in substantial quantities from aggregating platelets and metabolized during circulation to 11-dehydro TXB2 and 2,3-dinor TXB2.1 11-dehydro TXB2 is one of the main plasma metabolites of TXB2 and can be used as a marker for in vivoTXA2synthesis.1,2,3,4 The mean plasma level in human males is 0.9-4.3 pg/ml and the half life is 45-60 minutes.2,3,4 Urinary concentrations of 11-dehydro TXB2 are approximately 30-70 ng/mmol creatinine.5,6 |
别名 | 11-dehydro TXB2;11-keto TXB2; |
供应商 | Cayman |
应用文献 | |
1.Ciabattoni, G.,Pugliese, F.,Davi, G., et al. Fractional conversion of thromboxane B2 to urinary 11-dehydrothromboxane B2 in man. Biochimica et Biophysica Acta 992, 66-70 (1989). 2.Fitzgerald, G.A.,Lawson, J.,Blair, I.A., et al. Analysis of urinary metabolites of thromboxane and prostacyclin by negative-ion chemical-ionization gas chromatography/mass spectrometry. Advances in Prostaglandin, Thromboxane, and Leukotriene Research 15, 87-90 (1985). 3.Takasaki, W.,Nakagawa, A.,Tanaka, Y., et al. Enzyme immunoassay of human plasma 11-dehydrothromboxane B2. Thrombosis Research 63, 331-341 (1991). 4.Catella, F.,Healy, D.,Lawson, J.A., et al. 11-dehydro Thromboxane B2: A quantitative index of thromboxane A2 formation in the human circulation. Proceedings of the National Academy of Sciences of the United States of America 83, 5861-5865 (1986). 5.Lellouche, F.,Fradin, A.,FitzGerald, G., et al. Enzyme immunoassay measurement of the urinary metabolites of thromboxane A2 and prostacyclin. Prostaglandins 40, 297-310 (1990). 6.Perneby, C.,Granström, E.,Beck, O., et al. Optimization of an enzyme immunoassay for 11-dehydro-thromboxane B2 in urine: Comparison with GC-MS. Thrombosis Research 96, 427-436 (1999). | |
运输条件 | Wet ice in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥98% |
计算分子量 | 368.5 |
分子式 | C20H32O6 |
CAS号 | 67910-12-7 |
稳定性 | ≥ 1 year |
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