NBD-Fructose
货号：
9002314-10mg 基本售价：
13090.0 元 规格：
10 mg
产品信息
概述| 货号 | 9002314-10mg |
| 描述 | NBD-fructose is a fluorescently labeled fructose derivative that is used to monitor fructose uptake in normal and cancerous cells via fluorescence microscopy. It specifically accumulates in cells bearing GLUT5, a sugar transporter responsible for fructose transfer across cell membranes.1,2 Breast cancer cells are known to overexpress GLUT5 and high dietary fructose has been suggested to play a role in cancer metabolism and metabolic syndrome.1,2 Thus, NBD-fructose is a potentially useful tool for studying GLUT5 transport activity in certain cancer and metabolic conditions. |
| 别名 | 1-NBDF;1-(7-nitro-1,2,3-benzadiazole)-Fructose; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Levi, J.,Cheng, Z.,Gheysens, O., et al. Fluorescent fructose derivatives from imaging breast cancer cells. Bioconjug.Chem. 18(3), 628-634 (2007).
2.Tanasova, M.,Plutschack, M.,Muroski, M.E., et al. Fluorescent THF-based fructose analogue exhibits fructose-dependent uptake. ChemBioChem 14, 1263-1270 (2013).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% (sum of isomers) |
| 计算分子量 | 342.3 |
| 分子式 | C12H14N4O8 |
| CAS号 | 940961-04-6 |
| 稳定性 | ≥ 2 years |
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