| 货号 | 4355/50 |
| 别名 | 1-[(3S)-1-[4-(2-Benzofuranyl)-2-pyr |
| 供应商 | Tocris |
| 生物活性 | Potent, reversible inhibitor of fatty acid amide hydrolase (FAAH) (IC50 values are 28 and 100 nM for human and rat FAAH respectively). Noncovalent inhibitor; displays selectivity for FAAH over cannabinoid-related targets (IC50 > 20 μM for CB1, CB2 and TRPV1). Active in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 439.51 |
| 分子式 | C26H25N5O2 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| 参考文献 | Gustinet al (2011) Identification of potent, noncovalent fatty acid amide hydrolase (FAAH) inhibitors. Bioorg.Med.Chem.Lett. 21 2492. PMID: 21392988. Minet al (2011) Discovery and molecular basis of potent noncovalent inhibitors of fatty acid amide hydrolase (FAAH). Proc.Natl.Acad.Sci.U.S.A. 108 7379. PMID: 21502526. |