| 货号 | 3625/50 |
| 别名 | N-[(1,1-Dimethylethoxy)carbonyl]-L- |
| 供应商 | Tocris |
| 生物活性 | Potent and reversible human cathepsin L inhibitor (IC50 = 56 nM). Displays no inhibitory activity at cathepsin G. Antimalarial; inhibits leishmaniasis. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >97 % |
| 计算分子量 | 539.65 |
| 分子式 | C27H33N5O5 |
| 可溶性/溶解性 | Soluble to 50 mM in DMSO and to 10 mM in ethanol |
| 参考文献 | Myerset al (2008) Identification and synthesis of a unique thiocarbazate cathepsin L inhibitor. Bioorg.Med.Chem.Lett. 18 210. PMID: 18060772. Shahet al (2008) Kinetic characterization and molecular docking of a novel, potent and selective slow-binding inhibitor of human cathepsin L. Mol.Pharmacol. 74 34. PMID: 18403718. |