PTC 209 (50 MG)
货号：
5191/50 基本售价：
13077.2 元 规格：
50 mg
产品信息
概述| 货号 | 5191/50 |
| 别名 | N-(2,6-Dibromo-4-methoxyphenyl)-4-(2-methylimidazo[1,2-a]pyrimidin-3-yl)-2-thiazolamine |
性能| 供应商 | Tocris |
| 生物活性 | Bmi-1 inhibitor (IC50 ~ 0.5 μM); irreversibly impairs colorectal cancer-initiating cell (CIC) growth. Reduces tumor growth in CIC xenograft assays and results in reduced potential of colorectal cancer cells to initiate tumors in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 495.19 |
| 分子式 | C17H13Br2N5< |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 20 mM in ethanol |
| 参考文献 | Kresoet al (2014) Self-renewal as a therapeutic target in human colorectal cancer. Nat.Med. 20 29. PMID: 24292392. |
