PFI 4 (50 MG)
货号：
5576/50 基本售价：
13077.2 元 规格：
50 mg
产品信息
概述| 货号 | 5576/50 |
| 别名 | N-[2,3-Dihydro-1,3-dimethyl-2-oxo-6-(1-pyrrolidinyl)-1H-benzimidazol-5-yl]-2-methoxybenzamide |
性能| 供应商 | Tocris |
| 生物活性 | Potent and selective BRPF1 bromodomain inhibitor (IC50 = 80 nM). Exhibits >100-fold selectivity for BRPF1 over a panel of other bromodomains including BRPF2 (BRD1), BRPF3 and BRD4. Disrupts BRPF1 binding to histone H3.3. Cell permeable. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 380.44 |
| 分子式 | C21H24N4O3 |
| 可溶性/溶解性 | Soluble to 50 mM in DMSO and to 10 mM in ethanol |
| 参考文献 | Demontet al (2014) 1,3-Dimethyl Benzimidazolones are potent, selective inhibitors of the BRPF1 bromodomain. ACS Med.Chem.Lett. 5 1190. PMID: 25408830. |
