| 货号 | 4429/50 |
| 别名 | 2,7-Dihydro-2,7-dioxo-3H-naphtho[1, |
| 供应商 | Tocris |
| 生物活性 | Selective inhibitor of apoptosis signal-regulating kinase 1 (ASK1, MAP3K5) (IC50 = 3 μM, Ki = 500 nM). |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 319.31 |
| 分子式 | C19H13NO4 |
| 可溶性/溶解性 | Soluble to 10 mM in DMSO |
| 参考文献 | Volynetset al (2011) Identification of 3H-naphtho[1,2,3-de]quinoline-2,7-diones as inhibitors of apoptosis signal-regulating kinase 1 (ASK1). J.Med.Chem. 54 (8) 2680. PMID: 21449566. Buet al (2001) Synthesis and cytotoxic activity of 7-oxo-7H-dibenz[f,ij]isoquinoline and 7-oxo-7H-benzo[e]perimidine derivatives. J.Med.Chem. 44 (12) 2004. PMID: 11384245. |