货号 | 5171/50 |
别名 | 4-[2-[[(2-Hydroxyphenyl)methyl]amin |
供应商 | Tocris |
生物活性 | High affinity, selective 5-HT2A agonist (Ki = 1.3 nM). Exhibits 100-fold selectivity for 5-HT2A over 5-HT2C. Elicits head twitch behavior in mice. |
运输条件 | Blue Ice |
存放说明 | Ambient |
纯度 | >98 % |
计算分子量 | 348.82 |
分子式 | C18H20N2O3 |
可溶性/溶解性 | Soluble to 10 mM in water with sonication and to 100 mM in DMSO |
参考文献 | Fantegrossiet al (2014) Hallucinogen-like effects of 2-([2-(4-cyano-2,5-dimethoxyphenyl) ethylamino]methyl)phenol (25CN-NBOH), a novel N-benzylphenethylamine with 100-fold selectivity for 5-HT2A receptors, in mice. Psychopharmacology (Berl.) 232 1039. PMID: 25224567. Hansenet al (2014) Synthesis and structure-activity relationships of N-benzyl phenethylamines as 5-HT2A/2C agonists. ACS.Chem.Neurosci. 5 243. PMID: 24397362. |