IOX 2 (50 MG)
货号：
4451/50 基本售价：
13077.2 元 规格：
50 mg
产品信息
概述| 货号 | 4451/50 |
| 别名 | N-[[1,2-Dihydro-4-hydroxy-2-oxo-1-(phenylmethyl)-3-quinolinyl]carbonyl]glycine |
性能| 供应商 | Tocris |
| 生物活性 | Potent inhibitor of HIF-1α prolyl hydroxylase-2 (PHD2) (IC50 = 21 nM). Displays over 100-fold selectivity for PHD2 over factor inhibiting HIF-1 (FIH-1) and histone demethylases JMJD2A, JMJD2C, JMJD2E and JMJD3. Cell permeable. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 352.34 |
| 分子式 | C19H16N2O5 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| 参考文献 | Murrayet al (2010) Dipeptidyl-quinolone derivatives inhibit hypoxia inducible factor-1α prolyl hydroxylases-1, -2, and -3 with altered selectivity. J.Comb.Chem. 12 676. PMID: 20666436. |
