GSK 5959 (50 MG)
货号：
5385/50 基本售价：
13077.2 元 规格：
50 mg
产品信息
概述| 货号 | 5385/50 |
| 别名 | N-[2,3-Dihydro-1,3-dimethyl-2-oxo-6-(1-piperidinyl)-1H-benzimidazol-5-yl]-2-methoxybenzamide |
性能| 供应商 | Tocris |
| 生物活性 | Potent and selective BRPF1 bromodomain inhibitor (IC50 = 80 nM). Exhibits >100-fold selectivity for BRPF1 over a panel of 35 other bromodomains, including BRPF2/3 and BET family bromodomains. Inhibits BRPF1 interaction with histone H3.3. Cell permeable. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 394.47 |
| 分子式 | C22H26N4O3 |
| 可溶性/溶解性 | Soluble to 10 mM in DMSO with sonication |
| 参考文献 | Demontet al (2014) 1,3-dimethyl benzimidazolones are potent, selective inhibitors of the BRPF1 bromodomain. ACS Med.Chem.Lett. 5 1190. PMID: 25408830. |
