CYM 50308 (50 MG)
货号：
4678/50 基本售价：
13077.2 元 规格：
50 mg
产品信息
概述| 货号 | 4678/50 |
| 别名 | (2Z,5Z)-5-[[1-(2,4-Difluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]methylene]-2-[(2-methoxyethyl)imino]-3-methyl-4-thiazolidinone |
性能| 供应商 | Tocris |
| 生物活性 | Potent and selective sphingosine-1-phosphate receptor 4 (S1P4) agonist (EC50 values are 56 nM and 2100 nM for S1P4 and S1P5 receptors, respectively). Displays no activity at S1P1, S1P2 and S1P3 receptors at concentrations up to 25 μM. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 405.46 |
| 分子式 | C20H21F2N3 |
| 可溶性/溶解性 | Soluble to 10 mM in DMSO |
| 参考文献 | Urbanoet al (2011) Discovery, synthesis and SAR analysis of novel selective small molecule S1P4-R agonists based on a (2Z,5Z)-5-((pyrrol-3-yl)methylene)-3-alkyl-2-(alkylimino)thiazolidin-4-one chemotype. Bioorg.Med.Chem.Lett. 21 6739. PMID: 21982495. |
