| 货号 | 19521-25mg |
| 描述 | Lanosterol is a naturally-occurring sterol and biosynthetic precursor of several animal, fungal, and protozoan steroids, including cholesterol and ergosterol.1,2,3 Defects in the processing of lanosterol contribute to a wide variety of disorders, including the formation of cataracts.2,4 Similarly, certain fungicides act by blocking lanosterol processing by fungi.5,6 |
| 别名 | 8,24-Lanostadien-3β-ol;3β-hydroxy-8,24-Lanostadiene;NSC 60677; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Espenshade, P.J., and Hughes, A.L. Regulation of sterol synthesis in eukaryotes. Annual Review of Genetics 41, 401-427 (2007). 2.Clayton, P.T. Disorders of cholesterol biosynthesis. Archives of Disease in Childhood 78(2), 185-189 (1998). 3.Warrilow, A.G.,Melo, N.,Martel, C.M., et al. Expression, purification, and characterization of Aspergillus fumigatus sterol 14-a demethylase (CYP51) isoenzymes A and B. Antimicrobial Agents and Chemotherapy 54(10), 4225-4234 (2010). 4.Zhao, L.,Chen, X.J.,Zhu, J., et al. Lanosterol reverses protein aggregation in cataracts. Nature 523(7562), 607-611 (2015). 5.Asami, T.,Mizutani, M.,Shimada, U., et al. Triadimefon, a fungicidal triazole-type P450 inhibitor, induces brassinosteroid deficiency-like phenotypes in plants and binds to DWF4 protein in the brassinosteroid biosynthesis pathway. Biochemistry Journal 369 (Pt 1), 71-76 (2003). 6.Saag, M.S., and Dismukes, W.E. Azole antifungal agents: Emphasis on new triazoles. Antimicrobial Agents and Chemotherapy 32(1), 1-8 (1988). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 426.7 |
| 分子式 | C30H50O |
| CAS号 | 79-63-0 |
| 稳定性 | ≥ 2 years |
| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |