| 货号 | 0106/100 |
| 别名 | D-(-)-2-Amino-5-phosphonopentanoic acid |
| 供应商 | Tocris |
| 生物活性 | Widely used competitive NMDA antagonist. More active form of AP5. Also agonist at quisqualate-sensitized AP6 site where it is less potent than the L-isomer, L-AP5 (Cat. No. 0107). Also available as part of the Mixed NMDA Receptor Tocriset™ or as a mixed isomer DL-AP5 (Cat. No. 0105). |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 197.13 |
| 分子式 | C5H12NO5P |
| 可溶性/溶解性 | Soluble to 100 mM in water |
| CAS号 | 79055-68-8 |
| 参考文献 | Schulteet al (1994) Utilization of the resolved L-isomer fo 2-amino-6-phosphonohexanoic acid (L-AP6) as a selective agonist for a quisqualate-sensitized site in hippocampal CA1 pyramidal neurons. Brain Res. 649 203. PMID: 7953634. Davies and Watkins (1982) Actions of D and L forms of 2-amino-5-phosphonovalerate and 2-amino-4-phosphonobutyrate in the cat spinal cord. Brain Res. 235 378. PMID: 6145492. Evanset al (1982) The effect of a series of ω-phosphonic-α-carboxylic amino acids on electrically evoked and amino acid induced responses in isolated spinal cord preparations. Br.J.Pharmacol. 75 65. PMID: 7042024. |