| 货号 | 10818-100mg |
| 描述 | Coumarin boronic acid (CBA) (Item No. 14051) is a fluorescent probe that can be used to detect peroxynitrite (Item No. 81565), hypochlorous acid, and hydrogen peroxide.1,2,3 It reacts directly and rapidly with peroxynitrite at an exponentially faster rate (k = 1.1 μM/s) than hydrogen peroxide (k = 1.5 M/s) and moderately faster rate than hypochlorous acid.1,2 Peroxynitrite oxidizes CBA stoichiometrically at a 1:1 ratio into a fluorescent product that can be examined at an excitation of 332 nm and emission > 400 nm.3 The pinacolate ester of coumarin boronic acid can react with peroxynitrite, hypochlorous acid, and hydrogen peroxide in a similar manner to CBA, yet is formulated for improved solubility.1,2,3,4 |
| 别名 | CBA pinacolate ester;CBE; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Zielonka, J.,Sikora, A.,Hardy, M., et al. Boronate probes as diagnostic tools for real time monitoring of peroxynitrite and hydroperoxides. Chemical Research in Toxicology 25(9), 1793-1799 (2012). 2.Zielonka, J.,Zielonka, M.,Sikora, A., et al. Global profiling of reactive oxygen and nitrogen species in biological systems. The Journal of Biological Chemisty 287(5), 2984-2995 (2012). 3.Zielonka, J.,Sikora, J.,Joseph, J., et al. Peroxynitrite is the major species formed from different flux ratios of co-generated nitric oxide and superoxide. The Journal of Biological Chemisty 285(19), 14210-14216 (2010). 4.Du, L.,Li, M.,Zheng, S., et al. Rational design of a fluorescent hydrogen peroxide probe based on the umbelliferone fluorophore. Tetrahedron Letters 49(19), 3045-3048 (2008). | |
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 272.1 |
| 分子式 | C15H17BO4 |
| CAS号 | 190788-61-5 |
| 稳定性 | ≥ 2 years |
| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |